Contact Pharmaceutical Sciences

Interim Chair: Amy Parkhill
Email: aparkhill@sjfc.edu
Office: WEGPHR 338
Phone: (585) 385-7235

Research in the Pharmaceutical Sciences

Contributions to the Knowledge of Science

The Department of Pharmaceutical Sciences is continuously successful in obtaining external funding to support the research and scholarship of the faculty. Recently, two new laboratories have been constructed, one devoted to research in molecular pharmacology and one to pharmaceutical formulation studies.

The labs are equipped with modern instrumentation, including:

Formulations & Drug Stability

  • High performance liquid chromatography (HPLC) (Shimadzu)
  • UV/VIS spectroscopy (Cary 50)
  • Thermogravimetric Analysis (TGA) (TA Instruments)
  • Differential Scanning Calorimeter (DSC) (TA Instruments)
  • X-Ray Diffractometer (Bruker)
  • Moisture Sorption/Desorption Analyzer (TA Instruments)
  • Particle Size Analysis and Processing (Horiba)
  • USP Dissolution apparatus with Optic Fibers (Distek)
  • USP Dissolution apparatus (Vankel)
  • Incubator (Fisher Scientific)
  • Stability Chambers (Thermo Scientific)
  • Natoli Tablet Press
  • Rotary (ten-station) Tablet Press (SMI Piccola)
  • Diosna Wet Granulator
  • Retsch Ball Mill
  • Rotary Solvent Evaporator (buchi)
  • Twin Shell Dry Blender (PK)
  • Quadro Comil
  • Tap Density Apparatus (Varian)
  • Bulk Density Apparatus (Scott Volumeter)
  • Sonic Sifter (Advantech)
  • Sieve Shaker (Rotap)
  • Tablet Friabilator (Varian)
  • Tablet Hardness Tester (Varian)
  • Tablet Disintegration Tester (Varian)
  • True Density Pycnometer (Micromeritics)
  • Buchi Spray Dryer
  • VirTis Lyophilizer (SP Scientific)
  • pH Meter (mettler Toledo)
  • Heratherm Oven (Thermo Scientific)
  • Incubator Shaker (New Brunswick Scientific)
  • Unuator (CITO)
  • Ointment Mill (EXAKT)
  • Milli-Q Purified Water System (Millipore)

Molecular Pharmacology and Cell Biology

  • Real-time automated PCR
  • Electrophoresis
  • Zeiss fluorescence microscope
  • Radioisotope-based protein binding assays
  • Cell culture facilities and CO2 incubators
  • Airstream Class II biosafety hood
  • Refrigerated centrifuges
  • Low temperature (-80° C and liquid N2) storage
  • SpectraMax UV.Vis and Fluor microplate reader
  • Kodak imaging system
  • VersaDoc imaging system
  • Brandel cell harvester
  • Autoclave (Fisher Scientific)
  • Liquid Scintillation Analyzer (Perkin Elmer)
 

Additional facilities, such as gas chromatography-mass spectrometry, NMR, ultracentrifuge, cell culture facilities, small animal vivarium, and a cold storage room are available through collaboration with the departments of Biology and Chemistry.

View a 360° panorama of the Molecular Pharmacology and Cell Biology Lab

Student-Directed Research in Pharmaceutical Sciences

Numerous opportunities exist for student-directed research, including independent study, advanced practice rotations in research and/or academia, laboratory teaching assistants, and the Science Scholars Program in Biology and Chemistry. The following areas represent the variety of research being conducted in the Department:

Dr. Christine R. Birnie

  • Pignato A, Birnie CR. Analysis of Compounded Pharmaceutical Products to Teach the Importance of Quality in an Applied Pharmaceutics Laboratory Course. Am J Pharm Educ. 2014;78(3):61. doi: 10.5688/ajpe78361.
  • ORAL PRESENTATION: Birnie, Christine R. "Navigating the Drug Quality and Security Act: New Regulations and Recent Trends in Pharmacy Compounding." Pharmaceutical Society of Rochester (PSR), Rochester, NY, April, 27, 2014. ACPE # 0170-9999-14-031-L04-P.

Dr. Ramil Sapinoro

  • POSTER PRESENTATION: Sapinoro, Ramil; Krasnov, Boris; Lombardozzi, Mathew; and Caraballo, Maria, "Programming macrophage inflammation-resolution: The role of ω-3 polyunsaturated fatty acids" - LIPID MAPS Annual Meeting: Lipidomics Impact on Cell Biology, Inflammation and Metabolic Diseases, La Jolla, CA, 2015
  • ORAL PRESENTATION: "Topic of the Day: Oral Vaccines and Other Clinical Trial Updates" in conjunction with the Rochester Victory Alliance - Rochester Area Task Force on AIDS (RAFTA) General Meeting, Rochester, NY, 2015

Dr. Amy Parkhill

  • Parkhill, A. L., Mathews, J. L., Fearing, S. and Gainsburg, J. (2014). The Impact of a Transgender Panel Discussion in a Required Diversity Course for First-year Pharmacy Students. Am J Pharm Ed, 78 (4): 1-7.
  • Parkhill, A. L. (2013). Oral Mucositis and Stomatitis Associated with Conventional and Targeted Anticancer Therapy. J Pharmacovigilance. 1 (4): Article 112.

Prof. Anthony Corigliano

  • POSTER PRESENTATION: Using Inter-professional Education as a means to enhance Personal and Professional development. AACP Annual Meeting, July 2015, Arlington, VA

Dr. Jennifer Mathews

  • Lull ME and Mathews JL (2015) Online self-testing resources prepared by peer tutors as a formative assessment tool in pharmacology courses. AJPE. (Accepted).
  • Parkhill, A. L., Mathews, J. L., Fearing, S. and Gainsburg, J. (2014). The Impact of a Transgender Panel Discussion in a Required Diversity Course for First-year Pharmacy Students. Am J Pharm Ed, 78 (4): 1-7.

Dr. Fang Zhao

  • Rush SD, Kim SE, Hughes SE, Gilbert JM, Ciancaglini PP, Zhao F. Stability of Glutamate-Aspartate Cardioplegia Additive Solution in Polyolefin IV Bags. Hosp Pharm. 2015;50(6):522-5. doi: 10.1310/hpj5006-522.
  • Prohotsky DL, Juba KM, Zhao F. Formulation and stability of an extemporaneously compounded oral solution of chlorpromazine HCl. J Pain Palliat Care Pharmacother. 2014;28(4):367-70. doi: 10.3109/15360288.2014.969874.

Dr. Lipika Chablani

  • Akalkotkar A, Chablani L, Tawde SA, D'Souza C, D'Souza MJ. Development of a microparticulate prostate cancer vaccine and evaluating the effect of route of administration on its efficacy via the skin. J Microencapsul. 2015;32(3):281-9. doi: 10.3109/02652048.2015.1017615.
  • Chablani L, Mulla N and D'Souza MJ. Mucosal delivery of particulate breast cancer vaccine. Nanoparticulate Vaccine Delivery Systems, Pan Stanford Publishing. 2015; May: 171-185.

Dr. Vivek S. Dave

  • Dave VS, Chanda M, Sayles M, Popielarczyk M, Boyce H, Bompelliwar SK, et al. Correlation of Structural and Macroscopic Properties of Starches with Their Tabletability Using the SM2 Approach. Journal of pharmaceutical sciences. 2015; 104 (11):3870-82. doi: 10.1002/jps.24601.
  • Dave VS, Saoji SD, Raut NA, Haware RV. Excipient variability and its impact on dosage form functionality. Journal of pharmaceutical sciences. 2015; 104 (3):906-15. doi: 10.1002/jps.24299.

Dr. Melinda Lull

  • LULL, Melinda E; SLEVINSKI, Casey U; TRAINA, Andrea N. Self-directed learning through journal use in an elective pharmacy course. Pharmacy Education, [S.l.], v. 15, mar. 2015. ISSN 1477-2701.
  • Traina AN, Lull ME, Hui AC, Zahorian TM, Lyons-Patterson J. Once-Weekly Exenatide as Adjunct Treatment of Type 1 Diabetes Mellitus in Patients Receiving Continuous Subcutaneous Insulin Infusion Therapy. Canadian Journal of Diabetes. 2014;38(4):269-72. doi: http://dx.doi.org/10.1016/j.jcjd.2013.10.006.

Dr. Anand Sridhar

  • POSTER PRESENTATION: M. Zak, A. Corigliano, J. Souza, K. DelMonte, A. DiGiorgio, C. Birnie, S. Anand, Using Inter-professional Education as a means to enhance personal and professional development, American Association of Colleges of Pharmacy (AACP) Annual Meeting, National Harbor, MD (July 2015)
  • POSTER PRESENTATION: J. L. Mappus, S. Anand, Identification of plant-based environmental neurotoxins towards understanding the etiology of neurodegenerative disorders, American Society of Health Systems Pharmacists (ASHP), Annual Meeting, Anaheim, CA (December 2014)

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